Cancer is awful!! cancer can be, and must be prevented. how to avoid catching cancer? how to stop tumor before it starts? cancer prevention, cancer chemoprevention: avoid cancer, please, if someone loves you
Monday, January 24, 2011
Ther was, according to me, no book on food and cancer... no "good" book, except the huge WCRF-AICR 1997 and 2007 reports. Very interesting, and full of sicnece, but... too big for "normal" people. I am happy to tell you that Conner Middelmann-Whitney's book, entitled Zest for Life: The Mediterranean Anti-cancer Diet is really a "good" book: good science, good recipes. The only thing I disagree with is the insistance of Conner to advise "organic products" Nothing wrong with organic (les produits "Bio"), but no science behind to tell they prevent cancer. However, the remaining of this book is excellent, mostly extracted from the WCRF-AICR report. And the recipes are tasty and delicious
Could tomato (or lycopene) prevent prostate cancer?
The intake of cooked tomatoes, and the lycopene they contain, is associated with decreased risk of prostate cancer in several major epidemiological studies.
Rodents - In a fist animal model of prostate cancer, Imaida et al (2001) found no significant protection afforded by 15 to 45 ppm lycopene in dimethylaminobiphenol induced rats. However, a close look at their data shows that lycopene-fed rats had three-times less carcinoma than controls, in two independent studies (1/18 and 2/19 incidences vs. 8/23 in first study; 3/17 and 2/16 vs. 8/23 in second study). These data are consistent with a protection.
Boileau et al (2003) showed that freeze-dried tomato powder clearly protected the methylnitrosourea-testosterone-treated rats: the hazard ratio was 0.74 with 95%CI = 0.59 to 0.93. In contrast, 161 ppm lycopene had no effect (N.S. 9% decrease in mortality). The methylnitrosourea-testosterone treatment induces carcinoma in the dorsolateral and anterior prostate, which may be closer to human cancer than the ventral location induced by dimethylaminobiphenol. Further analysis of these data shows that tomato powder and pure lycopene significantly decreased the hazard risk for prostate cancer death by 56% and 44% respectively, after 45 wk (both p<0.05).>
Humans - No definitive clinical trial was done in humans yet. However, at least three small scale intervention studies were conducted in volunteers. Together, they give convincing evidence that tomato sauce, or lycopene, shrinks prostate cancer in humans.
H-1- The proportion of apoptotic cells increased three-fold in the prostate carcinoma of 32 patients given tomato sauce for 3 weeks (30 mg lycopene/d), compared with pre-treatment value (Kim, N&C 2003). However, the difference with control patients not given tomato did not reach significance. The same study shows that tomato sauce significantly reduced the level of serum prostate-specific antigen (PSA), and the level DNA oxidative damage in the prostate (Chen JNCI 2001; Bowen, EBM 2002). H-2- Fifteen prostate cancer patients given tomato oleoresin extract (30 mg lycopene/d) for 3 weeks had smaller tumors (80% vs. 45% less than 4 ml), and lower level of invasion of both prostatic and extra-prostatic tissues, compared with subjects in the control group (N=11). In addition, the intervention reduced PSA levels (Kucuk, CEBP 2001).
H-3- The third study involved 54 prostate cancer patients for two years. They all underwent orchidectomy, and half of them were given 4 mg lycopene/d via two capsules. Each LycoredTM capsule contains: lycopene 2mg, vitamin A palmitate 2500 I.U., alpha-tocopheryl acetate 10 I.U, vitamin C 50 I.U, zinc sulphate monohydrate 27.45 mg, monohydrated selenium dioxide 70 µg (Dr R.N. Gupta, personal communication). Several tumor markers, including PSA levels, uroflowmetry and bone scans were significantly improved in the lycopene group. Strikingly, 12 patients died in the control group, but seven only in the lycopene group (p<0.001)>
Conclusion on lycopene and prostate- These studies support the hypothesis that tomato reduces the risk of prostate cancer. No direct evidence is given that lycopene alone has chemopreventive properties. One rat study points out that whole tomato is protective, but not pure lycopene. Human studies were done with tomato sauce or extracts, or lycopene mixed with other antioxidant molecules. Animal and human studies fit together, but they were done simultaneously: In this ongoing success story, rodents studies were not "predictive", since rats results were not known before humans trial were set up.
Delicious anticancer recipe Easy and fast to make. For men
Delicious anticancer recipe quick to make for males.
Why for males, for men? because it prevents prostate cancer!
Tomato sauce anti prostate cancer
U need:
1- A can of contrated tomato (tomato paste) (140 g) and THE can opener!
2- Olive oil (half a glass)
3- Microwave oven (for two minutes!)
4- Glass jar (emptied of jam or marmalade)
Open the can, put paste in the jar, add olive oil, mix with a fork, cook for 1 minute in the oven, (mix again, cook 1 min again) repeat once or twice until it boils.
Delicious on rice or noodles
Nice also as a spread on bread if you are in a hurry!
How could this delicious paste be anticancer? Yes, red lycopen accumulates in men's prostate, and prevents micro-tumors development. Even, lycopen may kill cancer cells!
BUT if you drink a glass of tomato juice, or eat a tomato, lycopen will not be absorbed from the gut. It stays there, and go to the washroom!
BUT when tomatoes are cooked in oil, lycopen goes into the oil, which become "orange". Then when you eat it, the lycopen is absorbed, and goes into the blood, then into the prostate to make its good job.
Single diet - Many benefits. You do your best to avoid cancer, but… could theses efforts increase the risk of another major killer? No: the happy news is that what is good against cancer is good also against cardiovascular diseases, against diabetes, against obesity, and so on.
This is an interesting question: why are most illnesses prevented by the same way of life? Why is the active person, eating small portions, with many plant-based meals, living a longer and happier life than the sedentary obese meat-eater? May be we are "built" for this way of life. May be the TV-addicted is a biological non-sense. May be it is normal to search actively our food, and to eat many small portions of low-calories vegetables or fruits. Who knows? Whatever the answer, it is striking that even the NSAID can prevent the same range of illnesses, as shown on the chemoprevention database .
Do Frenchies get more or less cancers than American fellow? It depends on the cancer site.
Definitely more lung and neck cancers, thanks to killers light Si'Gret and strong Al'Cool.
But the hope is that it is changing… slowly. And French diet seems better than American one,
and French plates are (much) smaller, which makes a big difference!
I have tried another Blog site, quite nice too. I posted a blog on cancer chemoprevention in French. You still may want to have a look at the many dietary agents which were shown to help
cancer chemoprevention. Have a good meal! Denis
Do you know someone who has a cancer? Or someone who died too early with a bad tumor?
I do, and it is awfully sad to see those loving and beloved persons dying.
And as a society, can we afford to spend loads of money, of time, of energy, to struggle against a blind killer?
But we already know many things about this "bad guy":
Like Dracula, he hates garlic, and love tobacco smoke smell.
And good food can just repel cancer, so that it grow when you are … 150 years old!
Have a look at the many dietary agents which were shown to help
cancer chemoprevention,
And if it is not fast enough reach the mirror cancer prevention database.
This anticancer database is discussed on tumor free site.
And many good cancer researches are published in
Cancer Research, in
Carcinogenesis, particularly on
CRC prevention, and how
red meat might be implyed.
See also review papers in
CEBP, and in
Nutrition Cancer.
Last, have a look at the
NCI projects to help chemoprevention of colorectal cancer, and the abstract of the American Association for Cancer Research:
AACR Have a good day, and a great lunch! Do not awake cancer in your cells, but in contrast, slow it down so that it never emerges!
See you, Denis
